Building a backbone: Scientists recreate the body’s ‘GPS system’ in the lab

https://phys.org/news/2024-12-backbone-scientists-recreate-body-gps.html

By The Francis Crick Institute

Researchers have made a significant breakthrough by using a specific sequence of chemical signals to guide human stem cells into developing into a notochord. This is a key structure in early embryonic development, crucial for forming the backbone and spinal cord. By understanding and manipulating these signals, scientists can explore new avenues for regenerative medicine and treatments for spinal injuries or disorders. This innovative approach opens up exciting possibilities for advancing our understanding of human development and improving health outcomes.